HCID 19065244, compound → HCID 19049275, compound

Participants

Reaction Steps

2.4 g of the compound of Example 27 are hydrogenated in 40 ml of dimethylformamide with 100 mg of catalyst (5% palladium-on-carbon) under a hydrogen pressure of 6300 hPa. After absorption of the theoretical amount of hydrogen, the mixture is filtered over Millipore and the filtrate is distilled under reduced pressure. The residue yields 2.4 g of the expected product which is used as it is. An analytical sample was prepared by recrystallisation from isopropanol, m.p. 148° C.

Provenance & Evidence