3-Chlorophenylacetic acid → 2-(3-chlorophenyl)acetyl Chloride

Participants

Reaction Steps

To 3-chlorophenylacetic acid (51 g) was added thionyl chloride (100 ml) and N,N-dimethylforraamide (50 μl). After stirring at room temperature for 18 hours, the thionyl chloride was evaporated at reduced pressure. The residue was dissolved in toluene (60 ml) and again evaporated at reduced pressure to give 3-chlorophenylacetylchloride.

Provenance & Evidence