Hydrochloric Acid → HCID 54571277, compound

Alternatively, a solution of 5-(R)-acetoxy-1-ethoxyethoxyhexane (80 g, 0.34 mole) in ethyl lactate (150 ml) was stirred with 1M of aqueous hydrochloric acid solution (100 ml). After 4 hours, the layers were separated and the aqueous layer was saturated with sodium chloride and then extracted with ethyl lactate (4×75 ml). The combined organic layers were washed with saturated aqueous sodium bicarbonate solution (2×100 ml), dried over magnesium sulfate and the solvent evaporated under vacuum to give 5-(R)-acetoxy-1-hydroxyhexane (46 g, 83% yield).

1. customthe layers were separated
2. extractionextracted with ethyl lactate (4×75 ml)
3. washThe combined organic layers were washed with saturated aqueous sodium bicarbonate solution (2×100 ml)
4. dry with materialdried over magnesium sulfate
5. customthe solvent evaporated under vacuum

ORD record

ord-17ce44dc957b4317b44caef63e3a3ef7

Source dataset

uspto-grants-1997_05

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US05629423