HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 22872671, compound → HCID 22872662, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 22872671 | HCID 22872671 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Nickel | HCID 935 | — |
| Product | HCID 22872662 | HCID 22872662 | — |
Reaction Steps
5-Cyano-6-chloro-3-(1-BOC-2-(S)-azetidinylmethoxy)pyridine (0.26 g, 0.80 mmol) from step 92a was stirred in the presence of Raney nickel (0.047 g, 0.80 mmol) under 1 atm of hydrogen at room temperature for 2 hours. The mixture was filtered, and the solvent was removed to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05629325 |
| Source dataset | uspto-grants-1997_05 |
| ORD ID | ord-2c8c7e46d6c048c489098992cb0547bd |
| Source note | uspto-grants-1997_05 |