Methyl iodide → HCID 10784665, compound

Participants

Reaction Steps

A 435 mg portion of 2-(4-methyl-1-piperazinyl)benzoxazole was dissolved in 6 ml of DMF. Under cooling with ice, 0.19 ml of methyl iodide was added to the thus prepared solution, and the reaction was carried out for 1 hour at the same temperature and then for 1 hour at room temperature. The reaction solution was concentrated under a reduced pressure, and 4 ml of acetone was added to the resulting residue. The precipitate thus formed was collected by filtration, washed with acetone and then dried to obtain 670 mg of the title compound.

Provenance & Evidence