反应详情

A 540 mg portion of 2-(4-methyl-1-homopiperazinyl)-benzoxazole was dissolved in 5 ml of dichloromethane. Under cooling with ice, 0.32 ml of allyl iodide was added to the thus prepared solution, and the reaction was carried out for 1 hour at the same temperature and then for 1 hour at room temperature. The reaction solution was concentrated under a reduced pressure, and 5 ml of acetone was added to the resulting residue. The precipitate thus formed was collected by filtration, washed with acetone and then dried to obtain 821 mg of the title compound.

1. additionwas added to the thus prepared solution
2. waitfor 1 hour at room temperature
3. concentrationThe reaction solution was concentrated under a reduced pressure, and 5 ml of acetone
4. additionwas added to the resulting residue
5. customThe precipitate thus formed
6. filtrationwas collected by filtration
7. washwashed with acetone
8. customdried