HCID 19047729, compound → Methyl 3-amino-4-ethylbenzoate

HRID 1780819Notes

Reaction equation

HRID 1780819 reaction equation
[C:1]([C:4]1[CH:13]=[CH:12][C:7]([C:8]([O:10][CH3:11])=[O:9])=[CH:6][C:5]=1[N+:14]([O-])=O)(=O)[CH3:2]>CO.Cl.O>[NH2:14][C:5]1[CH:6]=[C:7]([CH:12]=[CH:13][C:4]=1[CH2:1][CH3:2])[C:8]([O:10][CH3:11])=[O:9]

Participants

4

Reactant 1

HCID 19047729HCID 19047729, compound

Product 1

HCID 13399999Methyl 3-amino-4-ethylbenzoate

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 21885828Hydrate;hydrochlorideSolvent

Procedure

The method described in Step 2. of Example 1 was applied to a solution of 35 (0.17 g) in methanol (20 mL) and 10% hydrochloric acid/water (5 mL) to prepare the above named compound. NMR (300 MHz, CDCl3) δ 7.40 (1H, d, J=8 Hz), 7.34 (1H, s), 7.10 (1H, d, J=8 Hz), 3.88 (3H, s), 3.71 (2H, b), 2.54 (2H, q, J=8 Hz), 1.26 (3H, t, J=8 Hz).

Workup

  1. customto prepare the

Sources & evidence

ORD record
ord-2e9ad006c0b44d42b5792a0cee082fac
Source dataset
uspto-grants-1997_05
Patent number
US05631280

Reaction notes

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