HCID 86750847, compound → Armillaramide

HRID 1780941Notes

Reaction equation

HRID 1780941 reaction equation
S(O)(O)(=O)=O.[OH:6][CH2:7][C@@H:8]([C@@H:10]([C@@H:12]([CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27])[OH:13])[OH:11])[NH2:9]>C(Cl)Cl.C(N(CC)CC)C>[C:7]([NH:9][C@H:8]([C@@H:10]([C@@H:12]([CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27])[OH:13])[OH:11])[CH2:7][OH:6])(=[O:6])[CH2:8][CH2:10][CH2:12][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25]

Participants

4

Reactant 1

HCID 86750847HCID 86750847, compound

Product 1

HCID 10506988Armillaramide

Reagents, catalysts & solvents 2

HCID 6344DichloromethaneSolventHCID 8471TriethylamineSolvent

Conditions

Temperature
25 °C

Procedure

After stirring for 25 minutes at 25° C., this above-described mixture is added to a pre-prepared stirred suspension containing 4.68 g (11.5 mmoles) of phytosphingosine sulphate (purity 82%) in 15 ml of methylene chloride and 2.1 ml of triethyl amine.

Workup

  1. additionthis above-described mixture is added to a pre-prepared
  2. stirringstirred suspension

Sources & evidence

ORD record
ord-d198ab03983249f3bb1a58d5cd3babbc
Source dataset
uspto-grants-1997_05
Patent number
US05631356

Reaction notes

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