4-Phenoxybenzaldehyde → HCID 19048166, compound

HRID 1781163Notes

Reaction equation

HRID 1781163 reaction equation
[O:1]([C:8]1[CH:15]=[CH:14][C:11]([CH:12]=O)=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:16][S:17][CH2:18][CH2:19][NH2:20]>>[CH3:16][S:17][CH2:18][CH2:19][NH:20][CH2:12][C:11]1[CH:14]=[CH:15][C:8]([O:1][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)=[CH:9][CH:10]=1

Participants

3

Reactant 2

HCID 661394-PhenoxybenzaldehydeHCID 87697(2-(Methylthio)ethyl)amine

Product 1

HCID 19048166HCID 19048166, compoundYield 93%

Procedure

Following the procedure described in Example 68A, 4-phenoxybenzaldehyde (1.98 g, 10 mmol) and 2-methylthioethylamine (0.912 g, 10 mmol) were combined to give the title compound (2.53 g, 93%) 1H NMR (300 MHz, CDCl3) δ 7.32 (m, 4 H), 7.09. (t, 1 H), 6.97 (m, 4 H), 3.80 (s, 2 H), 2.84 9t, 2 H), 2.68 (t, 2 H), 2.10 (s, 3 H).

Sources & evidence

ORD record
ord-9f45dad8c60d489d95c63e01bee5ba95
Source dataset
uspto-grants-1997_05
Patent number
US05631401

Reaction notes

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