Isopropanol → 2,2-Dimethyl-4-[6-(propan-2-ylamino)purin-9-yl]-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxole-6-carboxylic acid

HRID 178117Notes

Reaction equation

HRID 178117 reaction equation
[CH:24]([CH3:25])([CH3:26])[NH2:27].[CH:28]([OH:29])([CH3:30])[CH3:31].[Cl:1][c:2]1[c:3]2[n:4][cH:5][n:6]([CH:11]3[O:12][CH:13]([C:21](=[O:22])[OH:23])[CH:14]4[CH:15]3[O:16][C:17]([CH3:19])([CH3:20])[O:18]4)[c:7]2[n:8][cH:9][n:10]1>>[c:2]1([NH:27][CH:24]([CH3:25])[CH3:26])[c:3]2[n:4][cH:5][n:6]([CH:11]3[O:12][CH:13]([C:21](=[O:22])[OH:23])[CH:14]4[CH:15]3[O:16][C:17]([CH3:19])([CH3:20])[O:18]4)[c:7]2[n:8][cH:9][n:10]1

Participants

4

Reactant 3

HCID 3776IsopropanolHCID 6363IsopropylamineHCID 14374714(3aS,4S,6R,6aR)-6-(6-chloro-9H-purin-9-yl)-2,2-dimethyl-tetrahydro-2H-furo[3,4-d][1,3]dioxole-4-carboxylic acid

Product 1

HCID 234488402,2-Dimethyl-4-[6-(propan-2-ylamino)purin-9-yl]-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxole-6-carboxylic acid

Sources & evidence

ORD record
ord-cf1eece7b4f74a5d9f2718239ce6dc4a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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