Phenylacetaldehyde → HCID 11287511, compound

HRID 1781307Notes

Reaction equation

HRID 1781307 reaction equation
[CH2:1]([CH:8]1[NH:12][CH:11]([C:13]([OH:15])=[O:14])[CH2:10][S:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.N[C@H](C(O)=O)CS.C1(CC=O)C=CC=CC=1>>[CH2:1]([CH:8]1[NH:12][C@H:11]([C:13]([OH:15])=[O:14])[CH2:10][S:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 3

HCID 998PhenylacetaldehydeHCID 5862L-(+)-CysteineHCID 42851552-benzyl-1,3-thiazolidine-4-carboxylic Acid

Product 1

HCID 11287511HCID 11287511, compound

Procedure

F (2RS, 4R) -2-Benzyl-4-thiazolidinecarboxylic acid may be prepared in a manner similar to that described in Example 1E, but starting with 53.7 g of L-cysteine and 56.5 g of phenylacetaldehyde. 75.8 g of (2RS,4R)-2-benzyl-4-thiazolidinecarboxylic acid, melting point 200° C., are thereby obtained.

Sources & evidence

ORD record
ord-0864c7b521d14d7eb031a94545d74b0f
Source dataset
uspto-grants-1997_05
Patent number
US05633270

Reaction notes

Loading…