Hydrochloric Acid → HCID 19766242, compound

HRID 1781375Notes

Reaction equation

HRID 1781375 reaction equation
C([N:9]1[CH2:14][CH2:13][C:12]2([CH2:19][C:18](=[O:20])[C:17]3[CH:21]=[CH:22][CH:23]=[CH:24][C:16]=3[S:15]2)[CH2:11][CH2:10]1)(=O)C1C=CC=CC=1.[ClH:25]>C(O)C>[NH:9]1[CH2:14][CH2:13][C:12]2([CH2:19][C:18](=[O:20])[C:17]3[CH:21]=[CH:22][CH:23]=[CH:24][C:16]=3[S:15]2)[CH2:11][CH2:10]1.[ClH:25]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 19045254HCID 19045254, compound

Product 1

HCID 19766242HCID 19766242, compoundYield 92%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A solution of product from Step C (3.2 g, 0.0095 mol) in ethanol (50 ml) and 6 N HCl (50 ml) was heated at reflux. After 18 hours, the reaction was concentrated to dryness and the residue crystallized from ethanol to yield 2.9 g (92%) of product.

Workup

  1. temperatureat reflux
  2. concentrationthe reaction was concentrated to dryness
  3. customthe residue crystallized from ethanol

Sources & evidence

ORD record
ord-16fafd1fac294152bba99cdec776ba37
Source dataset
uspto-grants-1997_05
Patent number
US05633247

Reaction notes

Loading…