Hydrochloric Acid → HCID 19045245, compound

HRID 1781376Notes

Reaction equation

HRID 1781376 reaction equation
[SH:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[SH:8].[C:9]([N:17]1[CH2:22][CH2:21][C:20](=O)[CH2:19][CH2:18]1)(=[O:16])[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1.Cl.[O-]S([O-])(=O)=O.[Na+].[Na+]>C(Cl)Cl>[C:9]([N:17]1[CH2:22][CH2:21][C:20]2([S:8][C:3]3[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=3[S:1]2)[CH2:19][CH2:18]1)(=[O:16])[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 24436Sodium SulfateHCID 693701,2-BenzenedithiolHCID 90583N-Benzoyl-4-piperidone

Product 1

HCID 19045245HCID 19045245, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent2×

Procedure

500 mgs (3.52 mmol) of 1,2-dimercaptobenzene and 610 mgs (3.00 mmol) of N-benzoyl-4-piperidone were stirred in CH2Cl2 while anhydrous HCl gas was introduced Na2SO4 (2 grams) was added and the mixture stirred 15 hours. The mixture was diluted with CH2Cl2 filtered and washed with H2O, and 10% NaOH. The organics were dried (Na2SO4) and concentrated to a solid (yield 740 mgs).

Workup

  1. additionwas added
  2. filtrationfiltered
  3. washwashed with H2O, and 10% NaOH
  4. dry with materialThe organics were dried (Na2SO4)
  5. concentrationconcentrated to a solid (yield 740 mgs)

Sources & evidence

ORD record
ord-a4e3b11bcb904ad0ac7556437318ff19
Source dataset
uspto-grants-1997_05
Patent number
US05633247

Reaction notes

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