Methylamine → HCID 178484937, compound

HRID 1781393Notes

Reaction equation

HRID 1781393 reaction equation
[C:1]([NH:3][C:4](=[N:7][CH2:8][C:9]1[CH:14]=[CH:13][C:12]([CH2:15][CH2:16][OH:17])=[CH:11][CH:10]=1)SC)#[N:2].[CH3:18][NH2:19]>CO>[C:1]([NH:3][C:4]([NH:19][CH3:18])=[N:7][CH2:8][C:9]1[CH:14]=[CH:13][C:12]([CH2:15][CH2:16][OH:17])=[CH:11][CH:10]=1)#[N:2]

Participants

4

Reactant 2

HCID 6329MethylamineHCID 19045321Methyl N-cyano-N′-[[4-(2-hydroxyethyl)phenyl]methyl]carbamimidothioate

Product 1

HCID 178484937HCID 178484937, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A solution of 0.42 g (0.00168 mol) of N-cyano-N'-[4-(2-hydroxyethyl)benzyl]-S-methylisothiourea in 50 ml of methanol and 10 g of methylamine was stirred at room temperature overnight. Evaporation of the solvent gave the title compound.

Workup

  1. customEvaporation of the solvent

Sources & evidence

ORD record
ord-9c1c7be5dc37482b9254a181f9161fc1
Source dataset
uspto-grants-1997_05
Patent number
US05633247

Reaction notes

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