Propofol → HCID 18988690, compound

HRID 1781491Notes

Reaction equation

HRID 1781491 reaction equation
[CH3:1][CH:2]([C:4]1[CH:30]=[C:29](C(C)C)[CH:28]=[C:27]([CH:34]([CH3:36])[CH3:35])[C:5]=1[O:6][CH2:7][C:8]([C:10]1[C:11]([CH:24]([CH3:26])[CH3:25])=[C:12]([O:19][S:20](=[O:23])(=[O:22])[NH2:21])[C:13]([CH:16]([CH3:18])[CH3:17])=[CH:14][CH:15]=1)=[O:9])[CH3:3].C(C1C=C(C(C)C)C=C(C(C)C)C=1O)(C)C.C(C1C=CC=C(C(C)C)C=1O)(C)C>>[CH3:36][CH:34]([C:27]1[CH:28]=[CH:29][CH:30]=[C:4]([CH:2]([CH3:3])[CH3:1])[C:5]=1[O:6][CH2:7][C:8]([C:10]1[C:11]([CH:24]([CH3:25])[CH3:26])=[C:12]([O:19][S:20](=[O:22])(=[O:23])[NH2:21])[C:13]([CH:16]([CH3:17])[CH3:18])=[CH:14][CH:15]=1)=[O:9])[CH3:35]

Participants

4

Reactant 3

HCID 4943PropofolHCID 821582,4,6-TriisopropylphenolHCID 19046528HCID 19046528, compound

Product 1

HCID 18988690HCID 18988690, compound

Procedure

This compound was prepared in the same manner as for the title compound of Example 46, except that 2,4,6 - triisopropylphenol was replaced with 2,6-diisopropylphenol, mp 108°-110° C.

Sources & evidence

ORD record
ord-c90de5a21e584d9293ad7c521d8cc0db
Source dataset
uspto-grants-1997_05
Patent number
US05633287

Reaction notes

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