HuagongsheHuagongshe Chemistry Print Report · For research reference only
Selenium Dioxide → HCID 104763, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Selenium Dioxide | HCID 24007 | — |
| Reactant | Verrucarin A | HCID 6326658 | — |
| Product | HCID 104763 | HCID 104763 | — |
Reaction Steps
The trichothecene therapeutic agent 16-oxo verrucarin A is prepared by selenium dioxide oxidation of verrucarin A. The MAb hydrazide is then reacted with 16-oxo verrucarin A at 4° C. overnight with agitation, thereby yielding a unique Schiff base-linked targeting protein having the following structure: ##STR19##
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05633351 |
| Source dataset | uspto-grants-1997_05 |
| ORD ID | ord-ab73c212c79c45b8805584012da837d6 |
| Source note | uspto-grants-1997_05 |