Phenylhydrazine → HCID 21459168, compound

HRID 1781871Notes

Reaction equation

HRID 1781871 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:14]=[C:15]([N+:19]([O-:21])=[O:20])[C:16]=1[O:17][CH3:18])[C:6]([CH2:8][C:9]([O:11]CC)=O)=O.[C:22]1([NH:28][NH2:29])[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:6]2[CH2:8][C:9](=[O:11])[N:28]([C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=3)[N:29]=2)[CH:14]=[C:15]([N+:19]([O-:21])=[O:20])[C:16]=1[O:17][CH3:18]

Participants

3

Reactant 2

HCID 7516PhenylhydrazineHCID 19000175HCID 19000175, compound

Product 1

HCID 21459168HCID 21459168, compound

Procedure

10.0 g of ethyl (3,4-dimethoxy-5-nitrobenzoyl)acetate are reacted with 4.0 g of phenylhydrazine in analogy to Example 53a. After recrystallization from methylene chloride/ethanol, there is obtained 3-(3,4-dimethoxy-5-nitrophenyl)-1-phenyl-2-pyrazolin-5-one in the form of yellow crystals of m.p. 190°-192°.

Workup

  1. customAfter recrystallization from methylene chloride/ethanol

Sources & evidence

ORD record
ord-9913918bbe9e496484cda70119ac0bc8
Source dataset
uspto-grants-1997_05
Patent number
US05633371

Reaction notes

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