Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | 5-(2-Fluorophenyl)-1-(3-pyridinylsulfonyl)-1H-pyrrole-3-carboxaldehyde | HCID 86232932 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 86630998 | HCID 86630998 | — |
Reaction Steps
5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde (330 mg) was dissolved in N,N-dimethylformamide (30 mL), N-bromosuccinimide (356 mg) was added and the mixture was stirred at 80° C. for 2 hr. The reaction mixture was allowed to cool, a saturated aqueous sodium hydrogencarbonate solution was added, and the mixture was extracted with ethyl acetate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07498337B2 |
|---|
| Source dataset | uspto-grants-2009_03 |
|---|
| ORD ID | ord-494d2c9f157546e684ff11beeda4d33f |
|---|
| Source note | uspto-grants-2009_03 |
|---|
