Chloride → 2-(2,3-Difluoro-phenyl)-1-[5-(3-dimethylamino-prop-1-ynyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-ethanone
Reaction equation
[Al+3:17].[CH3:1][N:2]([CH2:3][C:4]#[C:5][c:6]1[cH:7][c:8]2[c:9]([n:10][cH:11]1)[nH:12][cH:13][cH:14]2)[CH3:15].[Cl-:16].[Cl-:18].[Cl-:19].[Cl:32][CH2:33][Cl:34].[F:20][c:21]1[c:22]([CH2:28][C:29](=[O:30])[Cl:31])[cH:23][cH:24][cH:25][c:26]1[F:27]>>[CH3:1][N:2]([CH2:3][C:4]#[C:5][c:6]1[cH:7][c:8]2[c:9]([n:10][cH:11]1)[nH:12][cH:13][c:14]2[C:29]([CH2:28][c:22]1[c:21]([F:20])[c:26]([F:27])[cH:25][cH:24][cH:23]1)=[O:30])[CH3:15]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-df3aab1cb06b4f77b8ad8af603839412
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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