HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hexahydro-1-methyl-4-[1-(phenylmethyl)-4-piperidinyl]-1H-1,4-diazepine → Hexahydro-1-methyl-4-(4-piperidinyl)-1H-1 4-diazepine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hexahydro-1-methyl-4-[1-(phenylmethyl)-4-piperidinyl]-1H-1,4-diazepine | HCID 18321160 | — |
| Catalyst | Palladium hydroxide | HCID 9942167 | — |
| Product | Hexahydro-1-methyl-4-(4-piperidinyl)-1H-1 4-diazepine | HCID 18321176 | — |
Reaction Steps
Prepared analogously to Example A3f) from hexahydro-1-methyl-4-[1-(phenylmethyl)-4-piperidinyl]-1H-1,4-diazepine by hydrogenolysis, but using Pearlman's catalyst instead of palladium/charcoal, in a quantitative yield. Colourless viscous oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07498325B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-94fcb51b47c845f0ae6891a69974f9e6 |
| Source note | uspto-grants-2009_03 |