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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1782792Generated: October 30, 2026

Methyl 4-hydroxy-3-({[3-(methoxycarbonyl)cyclohexyl]amino}carbonyl)benzoate → Methyl 4-{3-[4-(2-biphenyl-4-ylethyl)phenyl]propoxy}-3-({[3-(methoxycarbonyl)-cyclohexyl]amino}carbonyl)benzoate

https://huagongshe.com/reaction/1782792

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 4-hydroxy-3-({[3-(methoxycarbonyl)cyclohexyl]amino}carbonyl)benzoateHCID 57589182—
Reactant4-{2-[4-(3-Iodopropyl)phenyl]ethyl}biphenylHCID 69081390—
ProductMethyl 4-{3-[4-(2-biphenyl-4-ylethyl)phenyl]propoxy}-3-({[3-(methoxycarbonyl)-cyclohexyl]amino}carbonyl)benzoateHCID 57589234—

Reaction Steps

Preparation takes place in analogy to Example 22 from the (+)-B-enantiomer of methyl 4-hydroxy-3-({[3-(methoxycarbonyl)cyclohexyl]amino}carbonyl)benzoate (see Example IX, method 2) and 4-{2-[4-(3-iodopropyl)phenyl]ethyl}biphenyl.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07498460B2
Source datasetuspto-grants-2009_03
ORD IDord-03c1f59eee2746c194b6039abe4c9a88
Source noteuspto-grants-2009_03