HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylamine → HCID 24759022, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | HCID 24759018 | HCID 24759018 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 24759022 | HCID 24759022 | 99% |
Reaction Steps
To a saturated solution of dimethylamine in ethanol (2 mL), cooled at 5° C. under Ar, was added 3-[4-[2-(4-fluoro-1H-indol-3-yl)-2-oxoacetyl]piperazin1-yl]-4-isopropoxy-cyclobut-3-ene-1,2-dione (0.020 g, 0.048 mmol) and the mixture was then allowed to stir at room temperature for 2 h. The volatiles were then removed in vacuo to give the essentially pure title compound (0.019 g, 99%) as a white solid:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07501419B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-24fc9d4575e24c72add2703e98910e41 |
| Source note | uspto-grants-2009_03 |