反应详情

To a solution of crude 131 (1.58 g) in CH2Cl2 (25 mL) was added methanol (0.26 mL, 6.43 mmol). DCC (1.45 g, 7.02 mmol) and catalytic DMAP. The solution was stirred at room temperature overnight. The solution was then filtered through Celite and concentrated in vacuo. The crude product was purified by silica gel column chromatography, eluting with 20% EtOAc in hexanes, to yield pure 132.

1. filtrationThe solution was then filtered through Celite
2. concentrationconcentrated in vacuo
3. customThe crude product was purified by silica gel column chromatography
4. washeluting with 20% EtOAc in hexanes
5. customto yield pure 132