HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(2-Methyl-1H-imidazole-1-yl)-5-(trifluoromethyl)aniline → 4-methyl-N-[3-(2-methylimidazol-1-yl)-5-trifluoromethyl-phenyl]-3[4-(4-methylimidazol-1-yl)-pyrimidin-2-ylamino]-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(2-Methyl-1H-imidazole-1-yl)-5-(trifluoromethyl)aniline | HCID 66775711 | — |
| Reactant | 4-Methyl-3-[4-(4-methylimidazol-1-yl)pyrimidin-2-yl-amino]benzoic acid | HCID 68851196 | — |
| Product | 4-methyl-N-[3-(2-methylimidazol-1-yl)-5-trifluoromethyl-phenyl]-3[4-(4-methylimidazol-1-yl)-pyrimidin-2-ylamino]-benzamide | HCID 68852427 | — |
Reaction Steps
4-methyl-3-[4-(4-methylimidazol-1-yl)pyrimidin-2-yl-amino]benzoic acid and 3-(2-methylimidazol-1-yl)-5-trifluoromethyl-phenylamine prepared in Preparation 31 were used according to the similar procedure to Example 1 to give the titled compound as yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07501424B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-25707edd76fc43a589cfa82a58fed9c7 |
| Source note | uspto-grants-2009_03 |