反应详情

To 6.01 g (0.021 mmol) of (2-chloro-3,5-dimethoxy-phenyl)-carbamic acid tert-butyl ester was added 15 mL of trifluoroacetic acid. The reaction was stirred for 3 hours at room temperature, then concentrated in vacuo. The residue was made basic with a saturated solution of sodium bicarbonate, then extracted three times with dichloromethane. The combined dichloromethane layers were dried with magnesium sulfate and concentrated in vacuo to give 3.98 g of the title compound, which was used as is in the following example.

1. concentrationconcentrated in vacuo
2. extractionextracted three times with dichloromethane
3. dry with materialThe combined dichloromethane layers were dried with magnesium sulfate
4. concentrationconcentrated in vacuo