Diisopropylethylamine → HCID 178425042, compound

HRID 1783642Notes

Reaction equation

HRID 1783642 reaction equation
[Cl:1][C:2]1[CH:9]=[CH:8][CH:7]=[C:6]([CH3:10])[C:3]=1[CH2:4][NH2:5].[S:11]1[CH2:17][C:15](=[O:16])[NH:14][C:12]1=S.CCN(C(C)C)C(C)C>>[Cl:1][C:2]1[CH:9]=[CH:8][CH:7]=[C:6]([CH3:10])[C:3]=1[CH2:4][NH:5][C:12]1[S:11][CH2:17][C:15](=[O:16])[N:14]=1

Participants

4

Reactant 3

HCID 81531DiisopropylethylamineHCID 5217992-Chloro-6-methylbenzylamineHCID 1201546Rhodanine

Product 1

HCID 178425042HCID 178425042, compound

Procedure

Similar procedure as described in example 15a was used, starting with 2-chloro-6-methyl-benzylamine, rhodanine, mercuric chloride and DIEA to give 2-(2-chloro-6-methyl-benzylamino)-thiazol-4-one. LC-MS m/e 259 (MH+).

Sources & evidence

ORD record
ord-ef29e45a96734e8fa693f15b781c59b7
Source dataset
uspto-grants-2009_03
Patent number
US07501428B2

Reaction notes

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