Hydrochloric Acid → HCID 57463076, compound

Participants

Reaction Steps

The tert-butyl (3R)-3-({4-[6-(3-cyanophenyl)imidazo[2,1-b][1,3]thiazol-5-yl]pyrimidin-2-yl}amino)piperidine-1-carboxylate (2.90 g, 5.79 mmol) was dissolved in 20 mL of ethyl acetate and treated with 30 mL of 3.0 M HCl in ethyl acetate at room temperature (RT) overnight. Solid product was filtered, washed with ethyl acetate and dried under vacuum overnight to provide the title compound as a yellow solid. It was used without further purification. LCMS: 402 [M+H].

Provenance & Evidence