2-Amino-5-chloropyridine → HCID 66882856, compound

HRID 1784046Notes

Reaction equation

HRID 1784046 reaction equation
[CH2:1]([O:3][C:4]([C@H:6]1[CH2:10][C:9](=[CH2:11])[CH2:8][C@@H:7]1[C:12]([OH:14])=O)=[O:5])[CH3:2].[NH2:15][C:16]1[CH:21]=[CH:20][C:19]([Cl:22])=[CH:18][N:17]=1>>[CH2:1]([O:3][C:4]([C@H:6]1[CH2:10][C:9](=[CH2:11])[CH2:8][C@@H:7]1[C:12](=[O:14])[NH:15][C:16]1[CH:21]=[CH:20][C:19]([Cl:22])=[CH:18][N:17]=1)=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 661742-Amino-5-chloropyridineHCID 57590164HCID 57590164, compound

Product 1

HCID 66882856HCID 66882856, compoundYield 48%

Procedure

Starting from 41b, the title compound was prepared in 48% yield according to the procedure for example 1 and 2, step 2 using 2-amino-5-chloropyridine. MS: 309.1 (M+H)+.

Sources & evidence

ORD record
ord-443283d1e67e46c58576fc7b5ca5ccaa
Source dataset
uspto-grants-2009_03
Patent number
US07501413B2

Reaction notes

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