HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-2-fluoroaniline → 1-(4-amino-3-fluoro-phenyl)-4-benzyloxy-1H-pyridin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-2-fluoroaniline | HCID 123050 | — |
| Reactant | 4-Benzyloxy-2(1H)-pyridone | HCID 3607724 | — |
| Reactant | 1-(4-Amino-3-fluorophenyl)pyridin-2-one | HCID 22181548 | — |
| Product | 1-(4-amino-3-fluoro-phenyl)-4-benzyloxy-1H-pyridin-2-one | HCID 66882413 | — |
Reaction Steps
1-(4-Amino-3-fluoro-phenyl)-4-benzyloxy-1H-pyridin-2-one was prepared from 4-benzyloxy-1H-pyridin-2-one and 4-bromo-2-fluoroaniline in analogy to the procedure described for the preparation of 1-(4-amino-3-fluoro-phenyl)-1H-pyridin-2-one described in C. F. Bigge et al., patent application WO 2003045912. MS: 311 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07501413B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-34c53b7818264de3813ba31788b88df6 |
| Source note | uspto-grants-2009_03 |