HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 68863043, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 68858769 | HCID 68858769 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 68863043 | HCID 68863043 | — |
Reaction Steps
(S)-2-Tert-butoxycarbonylamino-3-[4-(4-tert-butyl-benzyloxy)-phenyl]-propionic acid methyl ester (290 mg, 0.66 mmol) was treated with 4 mL of 4N HCl in dioxane for 1 h at room temperature. The solvent was evaporated and the remaining solid triturated with diethyl ether to give (S)-2-amino-3-[4-(4-tert-butyl-benzyloxy)-phenyl]-propionic acid methyl ester-hydrochloride (214 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07501538B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-ecb8d9f7750b4a1a8f7c582587ef1cf5 |
| Source note | uspto-grants-2009_03 |