HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-5-nitropyridine → 3-Methyl-6-nitroimidazo[1,2-a]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-5-nitropyridine | HCID 77888 | — |
| Reactant | 2-Bromopropanal | HCID 350624 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 3-Methyl-6-nitroimidazo[1,2-a]pyridine | HCID 21827346 | — |
Reaction Steps
Operations similar to Production Example 1-(2) were conducted using 2-bromopropionaldehyde and 2-amino-5-nitropyridine. The solid whereupon obtained was suspended in ethyl acetate, and washed with saturated aqueous sodium hydrogencarbonate solution to provide the title compound as yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07504412B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-08e9c128559343a49cfbb57ed99de03f |
| Source note | uspto-grants-2009_03 |