2-Bromopyridine → 4-(2-Pyridyl)Benzoic Acid

HRID 1784738Notes

Reaction equation

[C:1]([C:4]1[CH:9]=[CH:8][C:7](B(O)O)=[CH:6][CH:5]=1)([OH:3])=[O:2].Br[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][N:15]=1>>[N:15]1[CH:16]=[CH:17][CH:18]=[CH:19][C:14]=1[C:7]1[CH:8]=[CH:9][C:4]([C:1]([OH:3])=[O:2])=[CH:5][CH:6]=1

Participants

Reactant 2

HCID 79732-Bromopyridine

HCID 3121834-Carboxyphenylboronic Acid

Product 1

HCID 8216924-(2-Pyridyl)Benzoic Acid

Procedure

Production Example 14 was repeated except that 4-carboxyphenylboronic acid and 2-bromopyridine were used, to provide the title compound as white solid.

Sources & evidence

ORD record: ord-273cf6a0dc324d5bb169ee6b263492f1
Source dataset: uspto-grants-2009_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07504412B2

Reaction notes

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