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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1784743Generated: October 27, 2026

4-Carboxyphenylboronic Acid → 4-[5-(Difluoromethoxy)-2-pyridyl]benzenecarboxylic acid

https://huagongshe.com/reaction/1784743

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Carboxyphenylboronic AcidHCID 312183—
Reactant2-Bromo-5-(difluoromethoxy)pyridineHCID 23120579—
Product4-[5-(Difluoromethoxy)-2-pyridyl]benzenecarboxylic acidHCID 23120513—

Reaction Steps

Operations similar to those of Production Example 14 were conducted using 4-carboxyphenylboronic acid and 2-bromo-5-(difluoromethoxy)pyridine, to provide the title compound as white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07504412B2
Source datasetuspto-grants-2009_03
ORD IDord-b62752ee596f4f8c86b7587014a8b2bd
Source noteuspto-grants-2009_03