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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1784744Generated: October 25, 2026

6-Chloronicotinic acid → 6-(4-Fluorophenyl)nicotinic acid

https://huagongshe.com/reaction/1784744

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Chloronicotinic acidHCID 79222—
Reactant4-Fluorophenylboronic acidHCID 285645—
Product6-(4-Fluorophenyl)nicotinic acidHCID 22730186—

Reaction Steps

Operations similar to those of Production Example 14 were conducted using 6-chloronicotinic acid and 4-fluorophenylboronic acid, to provide the title compound as white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07504412B2
Source datasetuspto-grants-2009_03
ORD IDord-d32d41c62af2483c8f0d709efb1581f4
Source noteuspto-grants-2009_03