HCID 23120553, compound → HCID 23120587, compound

Participants

Reaction Steps

To a methanol solution (20 ml) containing 2-isopropyl-6-nitroimidazo[1,2-a]pyridine hydrobromide (280 mg), 10% palladium-on-carbon (30 mg) was added, and inside the reaction system was substituted with hydrogen, followed by an hour's stirring at room temperature. The reaction liquid was filtered through Celite™. Concentrating the filtrate under reduced pressure, crude 6-amino-2-isopropylimidazo[1,2-a]pyridine hydrobromide (250 mg) was obtained.

Provenance & Evidence