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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1784752Generated: October 29, 2026

4'-(Trifluoromethyl)-[1,1'-biphenyl]-4-carboxylic acid → N-(2,3-dimethylimidazo[1,2-a]pyridin-6-yl)-4'-(trifluoromethyl)[1,1'-biphenyl]-4-carboxamide

https://huagongshe.com/reaction/1784752

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4'-(Trifluoromethyl)-[1,1'-biphenyl]-4-carboxylic acidHCID 2782719—
Reactant2,3-Dimethyl-6-nitroimidazo[1,2-a]pyridineHCID 23120523—
ProductN-(2,3-dimethylimidazo[1,2-a]pyridin-6-yl)-4'-(trifluoromethyl)[1,1'-biphenyl]-4-carboxamideHCID 11567719—

Reaction Steps

Conducting the operations similar to those of Example 1 using 2,3-dimethyl-6-nitroimidazo[1,2-a]pyridine and 4′-(trifluoromethyl)-[1,1′-biphenyl]-4-carboxylic acid, the title compound was obtained as white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07504412B2
Source datasetuspto-grants-2009_03
ORD IDord-a69300b5d7a74e068179e9b4bf9f57aa
Source noteuspto-grants-2009_03