HuagongsheHuagongshe Chemistry Print Report · For research reference only
4'-(Trifluoromethyl)-[1,1'-biphenyl]-4-carboxylic acid → HCID 23120563, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4'-(Trifluoromethyl)-[1,1'-biphenyl]-4-carboxylic acid | HCID 2782719 | — |
| Reactant | Hydrogen chloride-ethyl acetate | HCID 21866389 | — |
| Reactant | 2-Cyclopropyl-3-methyl-6-nitroimidazo[1,2-a]pyridine | HCID 23120516 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 23120563 | HCID 23120563 | — |
Reaction Steps
Operations similar to those of Example 1 were conducted using 2-cyclopropyl-3-methyl-6-nitroimidazo[1,2-a]pyridine and 4′-(trifluoromethyl)[1,1′-biphenyl]-4-carboxylic acid. The resulting solid was dissolved in ethyl acetate, followed by addition of 4N hydrochloric acid-ethyl acetate solution and concentration under reduced pressure. The title compound was obtained as white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07504412B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-67a716d4480145e18f502b905ad0f4c3 |
| Source note | uspto-grants-2009_03 |