4-(2-Pyridyl)Benzoic Acid → HCID 69057839, compound

HRID 1784766Notes

Reaction equation

HRID 1784766 reaction equation
[CH:1]1([C:4]2[N:5]=[C:6]3[CH:11]=[CH:10][C:9]([N+:12]([O-])=O)=[CH:8][N:7]3[C:15]=2[CH3:16])[CH2:3][CH2:2]1.[N:17]1[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=1[C:23]1[CH:28]=[CH:27][C:26]([C:29](O)=[O:30])=[CH:25][CH:24]=1.[ClH:32].C(OCC)(=O)C>C(OCC)(=O)C>[ClH:32].[CH:1]1([C:4]2[N:5]=[C:6]3[CH:11]=[CH:10][C:9]([NH:12][C:29](=[O:30])[C:26]4[CH:27]=[CH:28][C:23]([C:18]5[CH:19]=[CH:20][CH:21]=[CH:22][N:17]=5)=[CH:24][CH:25]=4)=[CH:8][N:7]3[C:15]=2[CH3:16])[CH2:3][CH2:2]1

Participants

5

Reactant 3

HCID 8216924-(2-Pyridyl)Benzoic AcidHCID 21866389Hydrogen chloride-ethyl acetateHCID 231205162-Cyclopropyl-3-methyl-6-nitroimidazo[1,2-a]pyridine

Product 1

HCID 69057839HCID 69057839, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

The title compound was obtained as white solid by conducting the operations similar to those of Example 1, using 2-cyclopropyl-3-methyl-6-nitroimidazo[1,2-a]pyridine and 4-(2-pyridyl)benzenecarboxylic acid. The resulting solid was dissolved in ethyl acetate, followed by addition of 4N hydrochloric acid-ethyl acetate solution and concentration under reduced pressure, to provide the title compound as white solid.

Sources & evidence

ORD record
ord-5705660825af490f91854d7019e6ba9d
Source dataset
uspto-grants-2009_03
Patent number
US07504412B2

Reaction notes

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