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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1784769Generated: October 29, 2026

4-[5-(Difluoromethoxy)-2-pyridyl]benzenecarboxylic acid → N-(2-cyclopropyl-3-methylimidazo[1,2-a]pyridin-6-yl)-4-[5-(difluoromethoxy)-2-pyridyl] benzamide

https://huagongshe.com/reaction/1784769

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-[5-(Difluoromethoxy)-2-pyridyl]benzenecarboxylic acidHCID 23120513—
Reactant2-Cyclopropyl-3-methyl-6-nitroimidazo[1,2-a]pyridineHCID 23120516—
ProductN-(2-cyclopropyl-3-methylimidazo[1,2-a]pyridin-6-yl)-4-[5-(difluoromethoxy)-2-pyridyl] benzamideHCID 23120584—

Reaction Steps

Conducting the operations similar to those of Example 1 using 2-cyclopropyl-3-methyl-6-nitroimidazo[1,2-a]pyridine and 4-[5-(difluoromethoxy)-2-pyridyl]benzenecarboxylic acid, the title compound was obtained as white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07504412B2
Source datasetuspto-grants-2009_03
ORD IDord-cee137feb6da4ccf9328aa7dec8e873c
Source noteuspto-grants-2009_03