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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1784771Generated: November 1, 2026

2-Cyclopropyl-3-methyl-6-nitroimidazo[1,2-a]pyridine → N-(2-cyclopropyl-3-methylimidazo[1,2-a]pyridin-6-yl)-3-fluoro-4'-(trifluoromethyl)[1,1'-biphenyl]-4-carboxamide

https://huagongshe.com/reaction/1784771

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Cyclopropyl-3-methyl-6-nitroimidazo[1,2-a]pyridineHCID 23120516—
Reactant3-Fluoro-4'-(trifluoromethyl)-[1,1'-biphenyl]-4-carboxylic acidHCID 23120527—
ProductN-(2-cyclopropyl-3-methylimidazo[1,2-a]pyridin-6-yl)-3-fluoro-4'-(trifluoromethyl)[1,1'-biphenyl]-4-carboxamideHCID 23120536—

Reaction Steps

Conducting the operations similar to those of Example 1 using 2-cyclopropyl-3-methyl-6-nitroimidazo[1,2-a]pyridine and 3-fluoro-4′-(trifluoromethyl)[1,1′-biphenyl]-4-carboxylic acid, the title compound was obtained as white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07504412B2
Source datasetuspto-grants-2009_03
ORD IDord-b566a84903c24897bebab23fb36e3eff
Source noteuspto-grants-2009_03