HuagongsheHuagongshe Chemistry Print Report · For research reference only
4'-(Trifluoromethyl)-[1,1'-biphenyl]-4-carboxylic acid → N-(2-cyclopropylimidazo[1,2-a]pyridin-6-yl)-4''-(trifluoromethyl)biphenyl-4-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4'-(Trifluoromethyl)-[1,1'-biphenyl]-4-carboxylic acid | HCID 2782719 | — |
| Reactant | 2-Cyclopropyl-6-nitroimidazo[1,2-a]pyridine hydrobromide | HCID 23120517 | — |
| Product | N-(2-cyclopropylimidazo[1,2-a]pyridin-6-yl)-4''-(trifluoromethyl)biphenyl-4-carboxamide | HCID 23120576 | — |
Reaction Steps
Operations similar to those of Example 1 were conducted using 2-cyclopropyl-6-nitroimidazo[1,2-a]pyridine hydrobromide and 4′-(trifluoromethyl)[1,1′-biphenyl]-4-carboxylic acid, to provide N-(2-cyclopropylimidazo[1,2-a]pyridin-6-yl)-4′-(trifluoromethyl)[1,1′-biphenyl]-4-carboxamide as white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07504412B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-c68a44aad67a41719d3f49522f7f6d59 |
| Source note | uspto-grants-2009_03 |