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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1785014Generated: October 29, 2026

4-Fluorophenylboronic acid → benzyl 4-ethyl-2-formyl-5-pyridin4-yl-1H-pyrrole-3-carboxylate

https://huagongshe.com/reaction/1785014

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluorophenylboronic acidHCID 285645—
Reactant(Pyridin-4-yl)boronic acidHCID 2734379—
ReactantBenzyl 4-ethyl-2-formyl-5-iodo-1H-pyrrole-3-carboxylateHCID 11349592—
Productbenzyl 4-ethyl-2-formyl-5-pyridin4-yl-1H-pyrrole-3-carboxylateHCID 11404851—

Reaction Steps

Following the procedures described in Example 5, replacing methyl 4-ethyl-2-formyl-5-iodo-1H-pyrrole-3-carboxylate with benzyl 4-ethyl-2-formyl-5-iodo-1H-pyrrole-3-carboxylate and 4-fluorophenylboronic acid with pyridin-4-ylboronic acid, the title compound was obtained. Proton NMR for the product was consistent with the title compound. HRMS (ES) exact mass calculated for C20H19N2O3 (M+H): 335.1390. Found 335.1402

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07504429B2
Source datasetuspto-grants-2009_03
ORD IDord-ef2f3a1ebf1c4899b9bf76d5b0421dab
Source noteuspto-grants-2009_03