5-Bromopyrimidine → 5-[2-(2-Chloro-4-pyrimidin-5-yl-phenyl)-1-hydroxy-1-trifluoromethyl-propyl]-3-methyl-3H-benzooxazol-2-one
Reaction equation
[Br:36][c:37]1[cH:38][n:39][cH:40][n:41][cH:42]1.[Cl:1][c:2]1[c:3]([CH:17]([C:18]([C:19]([F:20])([F:21])[F:22])([OH:23])[c:24]2[cH:25][cH:26][c:27]3[c:28]([n:29]([CH3:33])[c:30](=[O:32])[o:31]3)[cH:34]2)[CH3:35])[cH:4][cH:5][c:6]([B:8]2[O:9][C:10]([CH3:11])([CH3:12])[C:13]([CH3:14])([CH3:15])[O:16]2)[cH:7]1>>[Cl:1][c:2]1[c:3]([CH:17]([C:18]([C:19]([F:20])([F:21])[F:22])([OH:23])[c:24]2[cH:25][cH:26][c:27]3[c:28]([n:29]([CH3:33])[c:30](=[O:32])[o:31]3)[cH:34]2)[CH3:35])[cH:4][cH:5][c:6](-[c:37]2[cH:38][n:39][cH:40][n:41][cH:42]2)[cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-3d0ec65acafc4e9bafe0f5d29d0b4955
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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