Methane → tert-butyl N-ethyl-N-(1-pyrrolidin-3-ylcyclopropyl)carbamate

HRID 178526Notes

Reaction equation

[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]([CH2:9][CH3:10])[C:11]1([CH:14]2[CH2:15][N:16]([CH:19]([c:20]3[cH:21][cH:22][cH:23][cH:24][cH:25]3)[CH3:26])[CH2:17][CH2:18]2)[CH2:12][CH2:13]1.[C:30].[CH3:27][CH2:28][OH:29].[Pd:31]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]([CH2:9][CH3:10])[C:11]1([CH:14]2[CH2:15][NH:16][CH2:17][CH2:18]2)[CH2:12][CH2:13]1

Participants

Reactant 4

HCID 297Methane

HCID 702Ethanol

HCID 23938Palladium

HCID 67271933tert-butyl N-ethyl-N-[1-[1-(1-phenylethyl)pyrrolidin-3-yl]cyclopropyl]carbamate

Product 1

HCID 67270723tert-butyl N-ethyl-N-(1-pyrrolidin-3-ylcyclopropyl)carbamate

Sources & evidence

ORD record: ord-a31bc2caeb8444529b838933c86f01f7
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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