Ammonia → (3-Nitrophenyl)urea

HRID 1785307Notes

Reaction equation

HRID 1785307 reaction equation
[NH3:1].[N+:2]([C:5]1[CH:6]=[C:7]([N:11]=[C:12]=[O:13])[CH:8]=[CH:9][CH:10]=1)([O-:4])=[O:3]>>[N+:2]([C:5]1[CH:6]=[C:7]([NH:11][C:12]([NH2:1])=[O:13])[CH:8]=[CH:9][CH:10]=1)([O-:4])=[O:3]

Participants

3

Reactant 2

HCID 222AmmoniaHCID 768353-Nitrophenyl isocyanate

Product 1

HCID 3400496(3-Nitrophenyl)urea

Procedure

Ammonia was bubbled into a solution of 3-nitrophenylisocyanate (1.5 g, 9.1 mmol) for ten minutes. The reaction mixture was then concentrated and the resulting yellow solid was washed with ether (200 mL) to afford N-(3-nitrophenyl)-urea (1.35 g, 7.5 mmol).

Workup

  1. concentrationThe reaction mixture was then concentrated
  2. washthe resulting yellow solid was washed with ether (200 mL)

Sources & evidence

ORD record
ord-72664d7b391f4e4499752a268ef7893b
Source dataset
uspto-grants-2009_03
Patent number
US07504410B2

Reaction notes

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