[[(3-Nitrophenyl)amino]carbonyl]aminoacetic acid methyl ester → 3-(3-Aminophenyl)imidazolidine-2,4-dione

関与物質

反応手順

A suspension of [[[(3-nitrophenyl)amino]carbonyl]aminoacetic acid methyl ester (6.9 g, 27 mmol) in 6N aqueous hydrochloride solution (40 mL) and acetone (20 mL) was stirred at reflux overnight. The resulting solution was cooled and concentrated. The resulting yellowish suspension was filtered and the filter cake was washed with water (50 mL), aqueous sodium bicarbonate solution (50 mL), and air-dried to afford the title compound (4.4 g).

情報源と証拠