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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1785470Generated: October 25, 2026

1-(2-Phenethylamino-pyrimidin-4-yl)-8-phenyl-1,2,3,4-tetrahydro-pyrido[1,2-a]pyrimidin-6-one → HCID 11465507, compound

https://huagongshe.com/reaction/1785470

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-Phenethylamino-pyrimidin-4-yl)-8-phenyl-1,2,3,4-tetrahydro-pyrido[1,2-a]pyrimidin-6-oneHCID 11212397—
ReactantHCID 24721512HCID 24721512—
ProductHCID 11465507HCID 11465507—

Reaction Steps

Following the same procedure described for the synthesis of 1-(2-phenethylamino-pyrimidin-4-yl)-8-phenyl -1,2,3,4-tetrahydro-pyrido[1,2-a]pyrimidin-6-one, the sulfoxide (0.29 g, 0.83 mmol) was displaced with [3-(2-amino-propyl)-phenyl]-methanol (0.3 g, 1.66 mmol) to give the title compound as a light yellow solid. MS m/e 468 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07504403B2
Source datasetuspto-grants-2009_03
ORD IDord-ad8f2b2f8d6f40b8b539a6bde61a85d7
Source noteuspto-grants-2009_03