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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1785563Generated: October 29, 2026

8-{5-[4-(Trifluoromethyl)phenyl]oxazol-2-ylamino}-3,4-dihydronaphthalen-2(1H)-one → HCID 11964317, compound

https://huagongshe.com/reaction/1785563

Reaction equation

Participants

RoleNameHCIDCharge
Reactant8-{5-[4-(Trifluoromethyl)phenyl]oxazol-2-ylamino}-3,4-dihydronaphthalen-2(1H)-oneHCID 11955840—
ReactantHCID 11964315HCID 11964315—
ProductHCID 11964317HCID 11964317—

Reaction Steps

The title compound was prepared using the procedure as described in Example 2, substituting the product of Example 17C for the product of Example 1I. 1H NMR (DMSO-d6) δ 8.66 (s, 1H), 7.53 (d, J=7.8 Hz, 1H), 7.01 (t, J=7.8 Hz, 1H), 6.75 (d, J=7.5 Hz, 1H), 6.44 (s, 1H), 4.76 (d, J=3.7 Hz, 1H), 3.94 (m, 1H), 2.61-2.99 (m, 4H), 1.84 (m, 1H), 1.60 (m, 1H), 1.22 (s, 9H); MS (ESI+) m/z 287 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07504520B2
Source datasetuspto-grants-2009_03
ORD IDord-c7fa47d9c0bd4364964ee29cc9ebb1e2
Source noteuspto-grants-2009_03