O-Methyltyramine → HCID 68426881, compound

HRID 1785604Notes

Reaction equation

HRID 1785604 reaction equation
[CH3:1][O:2][C:3]1[CH:11]=[CH:10][C:6]([CH2:7][CH2:8][NH2:9])=[CH:5][CH:4]=1>CO>[CH3:1][O:2][C:3]1[CH:11]=[CH:10][C:6]([CH:7]([NH:9][CH2:8][CH2:7][C:6]2[CH:10]=[CH:11][C:3]([O:2][CH3:1])=[CH:4][CH:5]=2)[C:8]#[N:9])=[CH:5][CH:4]=1

Participants

3

Reactant 1

HCID 4657O-Methyltyramine

Product 1

HCID 68426881HCID 68426881, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Conditions

Temperature
125 °C

Procedure

4-Methoxyphenethylamine (1.2 mL, 8.2 mmol) and methanol (0.5 mL) are added to the crude material obtained above. The solution is heated to 125° C. for 15 minutes in a microwave reaction vessel after which the solution is concentrated in vacuo and the crude product obtained is used without further purification.

Workup

  1. customobtained above
  2. concentrationis concentrated in vacuo

Sources & evidence

ORD record
ord-6e0c65a18d89421a8b5bbe7682cd0650
Source dataset
uspto-grants-2009_03
Patent number
US07504517B2

Reaction notes

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