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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1785635Generated: October 30, 2026

4,4'-Dichlorobenzhydrol → 1-Benzhydryl-3-(4,4'-dichlorobenzhydryloxy)azetidine

https://huagongshe.com/reaction/1785635

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4,4'-DichlorobenzhydrolHCID 7033—
Reactant1-(Diphenylmethyl)azetidin-3-olHCID 330448—
Reactant1-Benzhydryl-3-(2,4,4'-trichlorobenzhydryloxy)azetidineHCID 68903818—
Product1-Benzhydryl-3-(4,4'-dichlorobenzhydryloxy)azetidineHCID 68903204—

Reaction Steps

This material was prepared from 1-benzhydryl-3-azetidinol (1) (45.0 mmol) and 4,4′-dichlorobenzhydrol (90.0 mmol) using the procedure described for compound (3) (8.6 g, 40%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07504522B2
Source datasetuspto-grants-2009_03
ORD IDord-9f45a528f3874963b37c93c375f2c487
Source noteuspto-grants-2009_03